Erscheinungsdatum: 15.10.2001Medium: TaschenbuchEinband: Kartoniert / BroschiertTitel: Protein Expression in Down Syndrome BrainAuflage: 2001 // 2001. 2001Autor: Lubec, GertVerlag: Springer-Verlag KGSprache: EnglischSchlagworte: Down-Syndrom // Mo
A stunning debut from an award-winning poet. Populating a small town in the Pacific Northwest, the characters in Lucia Perillo’s story collection all resist giving the world what it expects of them - and are surprised when the world comes roaring back. An addict trapped in a country house becomes obsessed with vacuum cleaners and the people who sell them door-to-door. An abandoned woman seeks consolation in tales of armed robbery told by one of her fellow suburban housewives. An accidental mother struggles to answer her daughter’s badgering about her paternity. And in three stories readers meet Louisa, a woman with Down syndrome who serves as an accomplice to her younger sister’s sexual exploits and her aging mother’s fantasies of revenge. Together, Happiness Is a Chemical in the Brain is a sharp-edged, witty testament to the ambivalence of emotions, the way they pull in directions that often cancel one another out or twist their subjects into knots. In lyrical prose, Perillo draws on her training as a naturalist and a poet to map the terrain of the comic and the tragic, asking how we mark the boundaries between these two zones. What’s funny, what’s heartbreaking, and who gets to decide? Lucia Perillo has published five books of poetry and a collection of essays. Her book Inseminating the Elephant won the Bobbitt Prize and was a finalist for the 2010 Pulitzer Prize in Poetry. Happiness Is a Chemical in the Brain is her first work of fiction. She lives in Olympia, Washington. 1. Language: English. Narrator: Carrington MacDuffie. Audio sample: http://samples.audible.de/bk/blak/005063de/bk_rhde_002536_sample.mp3. Digital audiobook in aax.
Ich betreue seit Jahren Kinder ab ca. 14 Monaten bis zu 14 Jahren. Studiert habe ich Psychologie und war jahrzehntelang in der Erwachsenenbildung tätig. Mein Sohn ist erwachsen und verheiratet. Ich bin im Ruhestand, verwitwet und zeitlich flexibel. Ich lache gern, liebe die Natur, die Musik und den Tanz. Klavierspielen kann ich für den Hausgebrauch (Kinderlieder, Weihnachtslieder). Mit behinderten Kindern (Down-Syndrom, minimal brain dysfunction usw.,) habe ich Erfahrung. Da ich vor Jahrzehnten aus Norddeutschland zugezogen bin spreche ich reines Hochdeutsch, verstehe aber alle deutschen Dialekte.
Attach electrodes to the fingers of five six-month-old babies. Then create new neural networks and program the brains of these children to process data at an extremely fast rate. Neuraldine is the corporation conducting this experiment to aid those with learning disabilities, one of which is handicapped with Downs Syndrome, (Number One). Nobody knew because there was no way to know that Number One was a savant. An undetectable rarity with Downs Syndromes children. The Children, numbered one through five, absorbed the data being fed to them at an amazing rate. As the children grew older, they became data addicted. Soon the Neuraldine Corp. could not obtain and feed the data at a rate required by the children and they rebelled. This story is enriched with physics (String Theory), neural networks, nuclear destruction, electromagnetic pulse attacks, as well as a worldwide plague. Number One is in charge. 1. Language: English. Narrator: Paul J McSorley. Audio sample: http://samples.audible.de/bk/acx0/022616de/bk_rhde_002536_sample.mp3. Digital audiobook in aax.
The study of the brain continues to expand at a rapid pace providing fascinating insights into the basic mechanisms underlying nervous system illnesses. New tools, ranging from genome sequencing to non-invasive imaging, and research fueled by public and private investment in biomedical research has been transformative in our understanding of nervous system diseases and has led to an explosion of published primary research articles. Diseases of the Nervous System summarizes the current state of basic and clinical knowledge for the most common neurological and neuropsychiatric conditions. In a systematic progression, each chapter covers either a single disease or a group of related disorders ranging from static insults to primary and secondary progressive neurodegenerative diseases, neurodevelopmental illnesses, illnesses resulting from nervous system infection and neuropsychiatric conditions. Chapters follow a common format and are stand-alone units, each covering disease history, clinical presentation, disease mechanisms and treatment protocols. Dr. Sontheimer also includes two chapters which discuss common concepts shared among the disorders and how new findings are being translated from the bench to the bedside. In a final chapter, he explains the most commonly used neuroscience jargon. The chapters address controversial issues in current day neuroscience research including translational research, drug discovery, ethical issues, and the promises of personalized medicine. This book provides an introduction for course adoption and an introductory tutorial for students, scholars, researchers and medical professionals interested in learning the state of the art concerning our understanding and treatment of diseases of the nervous system. Provides a focused tutorial introduction to the core diseases of the nervous system Includes comprehensive introductions to Stroke, Epilepsy, Alzheimers Disease, Parkinsons Disease, Huntingtons Disease, ALS, Head and Spinal Cord Trauma, Multiple Sclerosis, Brain Tumors, Depression, Schizophrenia and many other diseases of the nervous system Covers more than 40 diseases from the foundational science to the best treatment protocols Includes discussions of translational research, drug discovery, personalized medicine, ethics, and neuroscience Dr. Sontheimer is a researcher and educator with a life-long interest in Neuroscience. A native of Germany, he obtained a Masters degree in evolutionary comparative Neuroscience, where he worked on the development of occulomotor reflexes. In 1989, he obtained a doctorate in Biophysics and Cellular & Molecular Neuroscience form the University of Heidelberg studying biophysical changes that accompany the development of oligodendrocytes, the principle myelinating cells of the nervous system. He moved to the United States, where he later became a citizen, for post-doctoral studies at Yale University. His independent research career began at Yale in 1991 and continued at the University of Alabama Birmingham in 1994 and been focused on the role of glial support cells in health and disease. His laboratory has made major discoveries that led to two clinical trials using novel compounds to treat malignant gliomas. His research led to over 160 peer-reviewed publications. For the clinical development of his discoveries, Dr. Sontheimer started a biotechnologies company, Transmolecular Inc., which conducted both phase I and II clinical trials with the anti-cancer agent chlorotoxin. This technology was recently acquired by Morphotec Pharmaceuticals who will be conducting the phase III clinical trials. As educator, Dr. Sontheimer has been active in teaching Medical Neuroscience, graduate Cellular and Molecular Neuroscience, and, for the past 10 years, he has offered both graduate and undergraduate courses on Diseases of the Nervous System. In 2005, Dr. Sontheimer became director of the Civitan International Research Center, a philanthropically supported center devoted to the study and treatment of children with developmental disabilities, ranging from Downs syndrome to Autism. In this capacity, Dr. Sontheimer is frequently tasked explaining complex scientific processes to a lay audience. Recognizing the need to further educate the public about neurological disorders using language that is accessible to an educated public motivated Dr. Sontheimer to write a text book on Diseases of the Nervous system. To assure that the material is comprehensive yet readily